Search results for "calibration [detector]"
showing 10 items of 111 documents
Modular Breath Analyzer (MBA): Introduction of a Breath Analyzer Platform Based on an Innovative and Unique, Modular eNose Concept for Breath Diagnos…
2021
Exhaled breath analysis for early disease detection may provide a convenient method for painless and non-invasive diagnosis. In this work, a novel, compact and easy-to-use breath analyzer platform with a modular sensing chamber and direct breath sampling unit is presented. The developed analyzer system comprises a compact, low volume, temperature-controlled sensing chamber in three modules that can host any type of resistive gas sensor arrays. Furthermore, in this study three modular breath analyzers are explicitly tested for reproducibility in a real-life breath analysis experiment with several calibration transfer (CT) techniques using transfer samples from the experiment. The experiment …
Extractive Spectrophotometric Determination of Ondansetron by Ion-Pair Formation with Bromocresol Green
1996
Abstract An empirical spectrophotometric procedure for the determination of the antiemetic ondansetron is carried out. The method is based on the formation of a 1:1 ion pair with bromocresol green in the pH range over 3.2 – 4.4, extraction into chloroform layer and spectrophotometric measurement at 420.8 nm. The calibration graph is linear over the range 0.1 – 20 μg ml−1 ondansetron, with a relative standard deviation of 2.7%; the influence of foreign substances is also studied. The method is applied to ondansetron determination in human urine.
Continuous flow-injection-atomic absorption spectrometric method for the determination of Ondansetron
1995
Abstract A flow-injection procedure for the indirect determination of the new drug Ondansetron is proposed. The method is based on the reaction of the drug in an oxidative solid-phase reactor included in the flow assembly. The reactor was made by lead dioxide physically entrapped by polymerization; the released lead(II) was monitored by atomic absorption spectrometry at 217.0 nm. The procedure gave a linear calibration graph up to 20 μg ml−1 of Ondansetron with a sample throughput of 338 samples h−1.
Determination of sertraline in rat plasma by HPLC and fluorescence detection and its application toin vivopharmacokinetic studies
2012
A simple, rapid, and sensitive HPLC method based on 9H-fluoren-9-ylmethyl chloroformate derivatization for the quantification of sertraline in rat plasma has been developed, requiring a plasma sample of only 0.1 mL, which was deproteinized and derivatized for 5 min in two single steps. The obtained derivative was stable at room temperature and was determined by HPLC using a fluorescence detector. The analytical column was a C(18) column and the mobile phase was acetonitrile and water (80:20, v/v). Calibration curves were linear in the range of 10-500 ng/mL. The limit of detection was approximately 3 ng/mL, and the lower limit of quantification was established at 10 ng/mL. The bias of the me…
Results from a calibration of XENON100 using a source of dissolved radon-220
2017
A Rn 220 source is deployed on the XENON100 dark matter detector in order to address the challenges in calibration of tonne-scale liquid noble element detectors. We show that the Pb 212 beta emission can be used for low-energy electronic recoil calibration in searches for dark matter. The isotope spreads throughout the entire active region of the detector, and its activity naturally decays below background level within a week after the source is closed. We find no increase in the activity of the troublesome Rn 222 background after calibration. Alpha emitters are also distributed throughout the detector and facilitate calibration of its response to Rn 222 . Using the delayed coincidence of R…
Frameless Neuronavigation Applied to Endoscopic Neurosurgery
2000
Objective: We retrospectively analyzed the indications, surgical techniques, and applicability of frameless neuronavigation to endoscopic procedures in a heterogeneous group of 15 patients. Material and Methods: In 8 patients indications for surgery were cystic lesions, in 3 patients intraventricular tumors, and in 4 patients occlusive hydrocephalus. The mean age was 39 years (range 9 - 76 years). The follow-up period ranged from 5 - 24 months (mean 10 months). Frameless neuronavigation was accomplished with the “operating arm system” in 10 cases and with the “optical tracking system” in 5 cases (RADIONICS, Burlington, USA). Results: In all 15 cases, neuronavigation sufficiently provided an…
Application of integrative cloud point extraction and concentration for the analysis of polyphenols and alkaloids in mulberry leaves
2018
Abstract A simple and efficient method based on cloud point extraction and concentration combined with high performance liquid chromatography was developed for the simultaneous separation and determination of five target compounds (deoxynojirimycin, chlorogenic acid, rutin, isoquercitrin and astragalin) in mulberry leaves samples. Firstly, to obtain a high extraction rate, the ultrasound assisted extraction was developed on acid modified Triton X-114 system. Under the optimal conditions, the total maximum extraction yields of five target compounds reached 20.80 mg/g, which was superior to conventional solvent extraction. After the cloud point extraction and concentration, the HPLC analysis …
Spectrophotometric Determination of Hydralazine with 2-Hydroxy-1-naphthaldehyde in Pharmaceuticals
1991
Abstract A new extraction-spectrophotometric method for the determination of hydralazine, based on its reaction with 2-hydroxy-1-naphthaldehyde at 25 °C, is described. The calibration curve was linear between 0.4 and 6 mg/mL of hydralazine. The molar absorbtivity of the product at 408 nm is 40 900 L · mol − 1 · cm − 1 . The method described was applied to the analysis of hydralazine in pharmaceutical preparations containing reserpine, hydrochlorothiazide, bendrofluorthiazine, propranolol, and other substances. The agreement with the U.S.P. XXI method was satisfactory for tablets and injections, but not for pellets.
Evolution of emerging Fusarium mycotoxins contents throughout the shelf-life period of food
2014
which is cooked by steaming. It has been historically eaten in North African countries but nowadays its consumption is widely extended all around the world. As a cereal-based food, semolina is highly susceptible to contamination by mycotoxin-producing fungi. The presented procedure involves a modified QuEChERSbased extraction of 24 mycotoxins (15-ADON, 3-ADON, AFLAB1, AFLAB2, AFLAG1, AFLAG2, BEA, DON, DAS, ENA, ENA1, ENB, ENB1, FB1, FB2, FB3, FUSX, HT-2, NEO, NIV, OTA, STG, T2, ZEA) produced by Aspergillus, Penicillum and Fusarium fungi. The validation was performed by analyzing recovery samples at three different spiked concentrations with four replicates (n=4) at each concentration. Recov…
Development of direct elemental analysis for process control of nuclear materials manufacturing
2019
In order to optimize the quality control processes of uranium and plutonium metals from nuclear industry production lines, laser-induced breakdown spectroscopy (LIBS) appears as an efficient technique: it enables multi-element, fast and remote chemical analysis that require no sample preparation. Thus, the purpose of our work is to develop this technique towards the quantification of metal impurities in nuclear materials, with an analytical development achieved from surrogate materials. It follows another PhD thesis where a particular spectral band, Vacuum UltraViolet, has been chosen for its performance regarding the detection of several light elements in such materials. However, after per…